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Immortalization capacity of HPV types is inversely related to chromosomal instability
High-risk human papillomavirus (hrHPV) types induce immortalization of primary human epithelial cells. Previously we demonstrated that immortalization of human foreskin keratinocytes (HFKs) is HPV type dependent, as reflected by the presence or absence of a crisis period before reaching immortality....
Autores principales: | Schütze, Denise M., Krijgsman, Oscar, Snijders, Peter J.F., Ylstra, Bauke, Weischenfeldt, Joachim, Mardin, Balca R., Stütz, Adrian M., Korbel, Jan O., de Winter, Johan P., Meijer, Chris J.L.M., Quint, Wim G.V., Bosch, Leontien, Wilting, Saskia M., Steenbergen, Renske D.M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122336/ https://www.ncbi.nlm.nih.gov/pubmed/26993771 http://dx.doi.org/10.18632/oncotarget.8058 |
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