MicroRNA-mediated epigenetic targeting of Survivin significantly enhances the antitumor activity of paclitaxel against non-small cell lung cancer

Elevated expression of Survivin correlates with poor prognosis, tumor recurrence, and drug resistance in various human cancers, including non-small cell lung cancer (NSCLC). The underlying mechanism of Survivin upregulation in cancer cells remains elusive. To date, no Survivin-targeted therapy has b...

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Detalles Bibliográficos
Autores principales: Wang, Shuiliang, Zhu, Ling, Zuo, Weimin, Zeng, Zhiyong, Huang, Lianghu, Lin, Fengjin, Lin, Rong, Wang, Jin, Lu, Jun, Wang, Qinghua, Lin, Lingjing, Dong, Huiyue, Wu, Weizhen, Zheng, Kai, Cai, Jinquan, Yang, Shunliang, Ma, Yujie, Ye, Shixin, Liu, Wei, Yu, Yinghao, Tan, Jianming, Liu, Bolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122342/
https://www.ncbi.nlm.nih.gov/pubmed/27177222
http://dx.doi.org/10.18632/oncotarget.9264

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