Cargando…

Crosstalk between the HIF-1 and Toll-like receptor/nuclear factor-κB pathways in the oral squamous cell carcinoma microenvironment

Hypoxia is a prominent feature of the microenvironment of solid tumors and may contribute to tumor progression through the oxygen-sensitive transcriptional regulator hypoxia-inducible factor-1 (HIF-1). Chronic inflammation is another typical feature. Inflammatory mediators, including Toll-like recep...

Descripción completa

Detalles Bibliográficos
Autores principales:	Han, Shengwei, Xu, Wenguang, Wang, Zhiyong, Qi, Xiaofeng, Wang, Yufeng, Ni, Yanhong, Shen, Hao, Hu, Qingang, Han, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122348/ https://www.ncbi.nlm.nih.gov/pubmed/27191981 http://dx.doi.org/10.18632/oncotarget.9329

Ejemplares similares

Erratum: Metformin sensitizes the response of oral squamous cell carcinoma to cisplatin treatment through inhibition of NF-κB/HIF-1α signal axis
por: Qi, Xiaofeng, et al.
Publicado: (2017)

Metformin sensitizes the response of oral squamous cell carcinoma to cisplatin treatment through inhibition of NF-κB/HIF-1α signal axis
por: Qi, Xiaofeng, et al.
Publicado: (2016)

Prognostic Factors of Primary Intraosseous Squamous Cell Carcinoma (PIOSCC): A Retrospective Review
por: Wenguang, Xu, et al.
Publicado: (2016)

Functional Heterogeneity of Reelin in the Oral Squamous Cell Carcinoma Microenvironment
por: Zhang, Xinwen, et al.
Publicado: (2021)

A Novel Multimodal NIR-II Nanoprobe for the Detection of Metastatic Lymph Nodes and Targeting Chemo-Photothermal Therapy in Oral Squamous Cell Carcinoma
por: Wang, Yufeng, et al.
Publicado: (2019)

Overexpression of HIF-1α indicates a poor prognosis in tongue carcinoma and may be associated with tumour metastasis
por: ZHENG, YANG, et al.
Publicado: (2013)

NF‐κB and HIF crosstalk in immune responses
por: D'Ignazio, Laura, et al.
Publicado: (2015)

Large-Scale Identification of Lysine Crotonylation Reveals Its Potential Role in Oral Squamous Cell Carcinoma
por: Yin, Xiteng, et al.
Publicado: (2023)

Epiregulin reprograms cancer-associated fibroblasts and facilitates oral squamous cell carcinoma invasion via JAK2-STAT3 pathway
por: Wang, Yujia, et al.
Publicado: (2019)

Immunological suppression of head and neck carcinoma by dendritic cell tumor fusion vaccine
por: MOU, YONGBIN, et al.
Publicado: (2013)

Asparagine Synthetase-Mediated l-Asparagine Metabolism Disorder Promotes the Perineural Invasion of Oral Squamous Cell Carcinoma
por: Fu, Yong, et al.
Publicado: (2021)

Ki-67 is an independent prognostic marker for the recurrence and relapse of oral squamous cell carcinoma
por: Jing, Yue, et al.
Publicado: (2019)

Identification of Biological Functions and Prognostic Value of NNMT in Oral Squamous Cell Carcinoma
por: Zhang, Weixian, et al.
Publicado: (2022)

Multiperspective quantitative tumor–stroma ratio reveals histological areas associated with poor outcomes in oral squamous cell carcinoma
por: Wang, Shuai, et al.
Publicado: (2023)

Higher Ki67 expression in fibroblast like cells at invasive front indicates better clinical outcomes in oral squamous cell carcinoma patients
por: Jing, Yue, et al.
Publicado: (2018)

Toll-like receptor 2 is present in the microenvironment of oral squamous cell carcinoma
por: Ng, L K, et al.
Publicado: (2011)

Identification of Metabolism-Associated Biomarkers for Early and Precise Diagnosis of Oral Squamous Cell Carcinoma
por: Wang, Yuhan, et al.
Publicado: (2022)

Worst Pattern of Perineural Invasion Redefines the Spatial Localization of Nerves in Oral Squamous Cell Carcinoma
por: Fu, Yong, et al.
Publicado: (2021)

Rh type C-glycoprotein functions as a novel tumor suppressor gene by inhibiting tumorigenicity and metastasis in head and neck squamous cell carcinoma
por: Xu, Wenguang, et al.
Publicado: (2019)

CD38 Multi-Functionality in Oral Squamous Cell Carcinoma: Prognostic Implications, Immune Balance, and Immune Checkpoint
por: Ding, Zhuang, et al.
Publicado: (2021)

Antitumor effect of a Pt-loaded nanocomposite based on graphene quantum dots combats hypoxia-induced chemoresistance of oral squamous cell carcinoma
por: Wei, Zheng, et al.
Publicado: (2018)

In situ DESI-MSI lipidomic profiles of mucosal margin of oral squamous cell carcinoma
por: Yang, Xihu, et al.
Publicado: (2021)

In vivo migration of dendritic cells labeled with synthetic superparamagnetic iron oxide
por: Mou, Yongbin, et al.
Publicado: (2011)

Molecular Crosstalk Between MYC and HIF in Cancer
por: Li, Yanping, et al.
Publicado: (2020)

Epigenetic crosstalk between hypoxia and tumor driven by HIF regulation
por: Li, Tiansheng, et al.
Publicado: (2020)

The crosstalk between HIFs and mitochondrial dysfunctions in cancer development
por: Bao, Xingting, et al.
Publicado: (2021)

OXTR(High) stroma fibroblasts control the invasion pattern of oral squamous cell carcinoma via ERK5 signaling
por: Ding, Liang, et al.
Publicado: (2022)

TA-MSCs, TA-MSCs-EVs, MIF: their crosstalk in immunosuppressive tumor microenvironment
por: Zhang, Zhenghou, et al.
Publicado: (2022)

The migration of synthetic magnetic nanoparticle labeled dendritic cells into lymph nodes with optical imaging
por: Su, Hang, et al.
Publicado: (2013)

Targeting SYK of monocyte-derived macrophages regulates liver fibrosis via crosstalking with Erk/Hif1α and remodeling liver inflammatory environment
por: Chen, Xuejiao, et al.
Publicado: (2021)

Cellular crosstalk in atherosclerotic plaque microenvironment
por: Mahdinia, Elmira, et al.
Publicado: (2023)

Therapeutic antitumor efficacy of tumor-derived autophagosome (DRibble) vaccine on head and neck cancer
por: Su, Hang, et al.
Publicado: (2015)

Toll-Like Receptors in Liver Fibrosis: Cellular Crosstalk and Mechanisms
por: Yang, Ling, et al.
Publicado: (2012)

Effect of Dissection and Reconstruction of Palatal Muscles on Morphological Features and Ultrastructure of the Oral Musculature in Cats
por: Han, Wei, et al.
Publicado: (2016)

Lipid Droplet-Related PLIN2 in CD68(+) Tumor-Associated Macrophage of Oral Squamous Cell Carcinoma: Implications for Cancer Prognosis and Immunotherapy
por: He, Yijia, et al.
Publicado: (2022)

HSP90AB1 Promotes the Proliferation, Migration, and Glycolysis of Head and Neck Squamous Cell Carcinoma
por: Zhang, Hongbo, et al.
Publicado: (2022)

Prognostic factors of palatal mucoepidermoid carcinoma: a retrospective analysis based on a double-center study
por: Xu, Wenguang, et al.
Publicado: (2017)

Crosstalk in oxygen homeostasis networks: SKN-1/NRF inhibits the HIF-1 hypoxia-inducible factor in Caenorhabditis elegans
por: Feng, Dingxia, et al.
Publicado: (2021)

Regulation of Sox9 activity by crosstalk with nuclear factor-κB and retinoic acid receptors
por: Rockel, Jason S, et al.
Publicado: (2008)

Evolution-driven crosstalk between glioblastoma and the tumor microenvironment
por: Wu, Lingxiang, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_qml5ms5dphe2ual07kk6q7o470