The tumor suppressive miR-200b subfamily is an ERG target gene in human prostate tumors

The TMPRSS2-ERG fusion occurs in approximately 50% of prostate cancer (PCa), resulting in expression of the oncogenic ERG in the prostate. Because ERG is a transcriptional activator, we hypothesized that ERG-regulated genes contribute to PCa development. Since microRNA (miRNA) has crucial functions...

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Detalles Bibliográficos
Autores principales: Zhang, Zheng, Lanz, Rainer B, Xiao, Lijuan, Wang, Lei, Hartig, Sean M, Ittmann, Michael M, Feng, Qin, He, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122366/
https://www.ncbi.nlm.nih.gov/pubmed/27191272
http://dx.doi.org/10.18632/oncotarget.9366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122366/
https://www.ncbi.nlm.nih.gov/pubmed/27191272
http://dx.doi.org/10.18632/oncotarget.9366

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