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The tumor suppressive miR-200b subfamily is an ERG target gene in human prostate tumors
The TMPRSS2-ERG fusion occurs in approximately 50% of prostate cancer (PCa), resulting in expression of the oncogenic ERG in the prostate. Because ERG is a transcriptional activator, we hypothesized that ERG-regulated genes contribute to PCa development. Since microRNA (miRNA) has crucial functions...
Autores principales: | Zhang, Zheng, Lanz, Rainer B, Xiao, Lijuan, Wang, Lei, Hartig, Sean M, Ittmann, Michael M, Feng, Qin, He, Bin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122366/ https://www.ncbi.nlm.nih.gov/pubmed/27191272 http://dx.doi.org/10.18632/oncotarget.9366 |
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