Genetic heterogeneity in primary and relapsed mantle cell lymphomas: Impact of recurrent CARD11 mutations

The genetic mechanisms underlying disease progression, relapse and therapy resistance in mantle cell lymphoma (MCL) remain largely unknown. Whole-exome sequencing was performed in 27 MCL samples from 13 patients, representing the largest analyzed series of consecutive biopsies obtained at diagnosis...

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Detalles Bibliográficos
Autores principales: Wu, Chenglin, de Miranda, Noel FCC, Chen, Longyun, Wasik, Agata M., Mansouri, Larry, Jurczak, Wojciech, Galazka, Krystyna, Dlugosz-Danecka, Monika, Machaczka, Maciej, Zhang, Huilai, Peng, Roujun, Morin, Ryan D., Rosenquist, Richard, Sander, Birgitta, Pan-Hammarström, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122381/
https://www.ncbi.nlm.nih.gov/pubmed/27224912
http://dx.doi.org/10.18632/oncotarget.9500

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