Efficacy of CD46-targeting chimeric Ad5/35 adenoviral gene therapy for colorectal cancers

CD46 is a complement inhibitor membrane cofactor which also acts as a receptor for various microbes, including species B adenoviruses (Ads). While most Ad gene therapy vectors are derived from species C and infect cells through coxsackie-adenovirus receptor (CAR), CAR expression is downregulated in...

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Detalles Bibliográficos
Autores principales: Cho, Young-Suk, Do, Manh-Hung, Kwon, Se-Young, Moon, Changjong, Kim, Kwonseop, Lee, Keesook, Lee, Sang-Jin, Hemmi, Silvio, Joo, Young-Eun, Kim, Min Soo, Jung, Chaeyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122383/
https://www.ncbi.nlm.nih.gov/pubmed/27203670
http://dx.doi.org/10.18632/oncotarget.9427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122383/
https://www.ncbi.nlm.nih.gov/pubmed/27203670
http://dx.doi.org/10.18632/oncotarget.9427

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