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Efficacy of CD46-targeting chimeric Ad5/35 adenoviral gene therapy for colorectal cancers
CD46 is a complement inhibitor membrane cofactor which also acts as a receptor for various microbes, including species B adenoviruses (Ads). While most Ad gene therapy vectors are derived from species C and infect cells through coxsackie-adenovirus receptor (CAR), CAR expression is downregulated in...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122383/ https://www.ncbi.nlm.nih.gov/pubmed/27203670 http://dx.doi.org/10.18632/oncotarget.9427 |