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Cabazitaxel operates anti-metastatic and cytotoxic via apoptosis induction and stalls brain tumor angiogenesis
Taxanes target microtubules and are clinically established chemotherapeutic agents with proven efficacy in human cancers. Cabazitaxel (XRP-6258, Jevtana®) is a second generation semisynthetic taxane with high chemotherapeutic potential in prostate cancer. There, cabazitaxel can overcome docetaxel-re...
Autores principales: | Ghoochani, Ali, Majernik, Gökce Hatipoglu, Sehm, Tina, Wach, Sven, Buchfelder, Michael, Taubert, Helge, Eyupoglu, Ilker Y., Savaskan, Nicolai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122391/ https://www.ncbi.nlm.nih.gov/pubmed/27203678 http://dx.doi.org/10.18632/oncotarget.9439 |
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