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ChREBP promotes the differentiation of leukemia-initiating cells to inhibit leukemogenesis through the TXNIP/RUNX1 pathways
Targeting leukemia-initiating cells (LICs) is the key to eradicating leukemia and preventing its relapse. Recent studies have indicated that metabolic regulation may play a critical role in the maintenance of stemness in LICs, although the detailed mechanisms are poorly understood. Herein, we provid...
Autores principales: | Zeng, Hongxiang, Gu, Hao, Chen, Chiqi, Li, Minle, Xia, Fangzhen, Xie, Li, Liu, Xiaoye, Zhang, Feifei, Tong, Xuemei, Wang, Jiangbo, Yu, Zhuo, Zheng, Junke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122394/ https://www.ncbi.nlm.nih.gov/pubmed/27224916 http://dx.doi.org/10.18632/oncotarget.9520 |
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