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Validation of a multi-omics strategy for prioritizing personalized candidate driver genes

Significant heterogeneity between different tumors prevents the discovery of cancer driver genes, especially in a patient-specific manner. We previously prioritized five personalized candidate mutation-driver genes in a hyper-mutated hepatocellular carcinoma patient using a multi-omics strategy. How...

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Detalles Bibliográficos
Autores principales: Liang, Li, Song, Liting, Yang, Yi, Tian, Ling, Li, Xiaoyuan, Wu, Songfeng, Huang, Wenxun, Ren, Hong, Tang, Ni, Ding, Keyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122402/
https://www.ncbi.nlm.nih.gov/pubmed/27469031
http://dx.doi.org/10.18632/oncotarget.9540