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Alterations of androgen receptor-regulated enhancer RNAs (eRNAs) contribute to enzalutamide resistance in castration-resistant prostate cancer
Enzalutamide is a second-generation anti-androgen for treatment of castration-resistant prostate cancer (CPRC). It prolongs survival of CRPC patients, but its overall survival benefit is relatively modest (4.8 months) and by 24 months most patients progress on enzalutamide. To date, however, the mol...
Autores principales: | Zhao, Jingwen, Zhao, Yu, Wang, Liguo, Zhang, Jun, Karnes, R. Jeffrey, Kohli, Manish, Wang, Guixia, Huang, Haojie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122410/ https://www.ncbi.nlm.nih.gov/pubmed/27221037 http://dx.doi.org/10.18632/oncotarget.9535 |
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