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Rare SNPs in receptor tyrosine kinases are negative outcome predictors in multiple myeloma

Multiple myeloma (MM) is a plasma cell disorder that is characterized by a great genetic heterogeneity. Recent next generation sequencing studies revealed an accumulation of tumor-associated mutations in receptor tyrosine kinases (RTKs) which may also contribute to the activation of survival pathway...

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Detalles Bibliográficos
Autores principales: Keppler, Sarah, Weiβbach, Susann, Langer, Christian, Knop, Stefan, Pischimarov, Jordan, Kull, Miriam, Stühmer, Thorsten, Steinbrunn, Torsten, Bargou, Ralf, Einsele, Hermann, Rosenwald, Andreas, Leich, Ellen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122427/
https://www.ncbi.nlm.nih.gov/pubmed/27246973
http://dx.doi.org/10.18632/oncotarget.9607