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Hyperglycemia-associated alterations in cellular signaling and dysregulated mitochondrial bioenergetics in human metabolic disorders

PURPOSE: The severity of untreated or refractory diabetes mellitus has been functionally linked to elevated concentrations of free plasma glucose, clinically defined as hyperglycemia. Operationally, the pathophysiological presentations of prolonged hyperglycemia may be categorized within insulin-dep...

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Autors principals: Stefano, George B., Challenger, Sean, Kream, Richard M.
Format: Online Article Text
Idioma:English
Publicat: Springer Berlin Heidelberg 2016
Matèries:
Accés en línia:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122622/
https://www.ncbi.nlm.nih.gov/pubmed/27084094
http://dx.doi.org/10.1007/s00394-016-1212-2