Proton Pump Inhibitors Display Antitumor Effects in Barrett's Adenocarcinoma Cells

Recent evidence has reported that proton pump inhibitors (PPIs) can exert antineoplastic effects through the disruption of pH homeostasis by inhibiting vacuolar ATPase (H(+)-VATPase), a proton pump overexpressed in several tumor cells, but this aspect has not been deeply investigated in EAC yet. In...

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Detalles Bibliográficos
Autores principales: Chueca, Eduardo, Apostolova, Nadezda, Esplugues, Juan V., García-González, María A., Lanas, Ángel, Piazuelo, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122752/
https://www.ncbi.nlm.nih.gov/pubmed/27932981
http://dx.doi.org/10.3389/fphar.2016.00452

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122752/
https://www.ncbi.nlm.nih.gov/pubmed/27932981
http://dx.doi.org/10.3389/fphar.2016.00452

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