Virus infection drives IL-2 antibody complexes into pro-inflammatory agonists in mice

The use of IL-2/JES6-1 Ab complex (IL-2 Ab Cx) has been considered as a potential therapeutic for inflammatory diseases due to its selective expansion of regulatory T cells (Tregs) in mice. Here, IL-2 Ab Cx was explored as a therapeutic agent to reduce joint inflammation induced by chikungunya virus...

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Detalles Bibliográficos
Autores principales: Lee, Wendy W. L., Teo, Teck-Hui, Lum, Fok-Moon, Andiappan, Anand K., Amrun, Siti Naqiah, Rénia, Laurent, Rötzschke, Olaf, Ng, Lisa F. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122839/
https://www.ncbi.nlm.nih.gov/pubmed/27886209
http://dx.doi.org/10.1038/srep37603

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122839/
https://www.ncbi.nlm.nih.gov/pubmed/27886209
http://dx.doi.org/10.1038/srep37603

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