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Statistical power considerations in genotype-based recall randomized controlled trials

Randomized controlled trials (RCT) are often underpowered for validating gene-treatment interactions. Using published data from the Diabetes Prevention Program (DPP), we examined power in conventional and genotype-based recall (GBR) trials. We calculated sample size and statistical power for gene-me...

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Detalles Bibliográficos
Autores principales:	Atabaki-Pasdar, Naeimeh, Ohlsson, Mattias, Shungin, Dmitry, Kurbasic, Azra, Ingelsson, Erik, Pearson, Ewan R., Ali, Ashfaq, Franks, Paul W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122840/ https://www.ncbi.nlm.nih.gov/pubmed/27886175 http://dx.doi.org/10.1038/srep37307

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