Epigenetic Enhancement of the Post-replicative DNA Mismatch Repair of Mammalian Genomes by a Hemi-(m)CpG-Np95-Dnmt1 Axis

DNA methylation at C of CpG dyads ((m)CpG) in vertebrate genomes is essential for gene regulation, genome stability and development. We show in this study that proper functioning of post-replicative DNA mismatch repair (MMR) in mammalian cells relies on the presence of genomic (m)CpG, as well as on...

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Detalles Bibliográficos
Autores principales: Wang, Keh-Yang, Chen, Chun-Chang, Tsai, Shih-Feng, Shen, Che-Kun James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122852/
https://www.ncbi.nlm.nih.gov/pubmed/27886214
http://dx.doi.org/10.1038/srep37490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122852/
https://www.ncbi.nlm.nih.gov/pubmed/27886214
http://dx.doi.org/10.1038/srep37490

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