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Physical Activity, Energy Expenditure, and Defense of Body Weight in Melanocortin 4 Receptor-Deficient Male Rats

Melanocortin 4 receptor (MC4R) variants contribute to human obesity, and rats lacking functional MC4R (Mc4r(K314X/K314X)) are obese. We investigated the hypothesis that low energy expenditure (EE) and physical activity contribute to this obese phenotype in male rats, and determined whether lack of f...

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Detalles Bibliográficos
Autores principales:	Almundarij, Tariq I., Smyers, Mark E., Spriggs, Addison, Heemstra, Lydia A., Beltz, Lisa, Dyne, Eric, Ridenour, Caitlyn, Novak, Colleen M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122857/ https://www.ncbi.nlm.nih.gov/pubmed/27886210 http://dx.doi.org/10.1038/srep37435

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