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Structural insights into the interaction of the ribosomal P stalk protein P2 with a type II ribosome-inactivating protein ricin
Ricin is a type II ribosome-inactivating protein (RIP) that depurinates A(4324) at the sarcin-ricin loop of 28 S ribosomal RNA (rRNA), thus inactivating the ribosome by preventing elongation factors from binding to the GTPase activation centre. Recent studies have disclosed that the conserved C-term...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122897/ https://www.ncbi.nlm.nih.gov/pubmed/27886256 http://dx.doi.org/10.1038/srep37803 |