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MC5r and A2Ar Deficiencies During Experimental Autoimmune Uveitis Identifies Distinct T cell Polarization Programs and a Biphasic Regulatory Response

Autoantigen-specific regulatory immunity emerges in the spleen of mice recovering from experimental autoimmune uveitis (EAU), a murine model for human autoimmune uveoretinitis. This regulatory immunity provides induced tolerance to ocular autoantigen, and requires melanocortin 5 receptor (MC5r) expr...

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Detalles Bibliográficos
Autores principales:	Lee, Darren J., Preble, Janine, Lee, Stacey, Foster, C. Stephen, Taylor, Andrew W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122918/ https://www.ncbi.nlm.nih.gov/pubmed/27886238 http://dx.doi.org/10.1038/srep37790

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