Cargando…

MC5r and A2Ar Deficiencies During Experimental Autoimmune Uveitis Identifies Distinct T cell Polarization Programs and a Biphasic Regulatory Response

Autoantigen-specific regulatory immunity emerges in the spleen of mice recovering from experimental autoimmune uveitis (EAU), a murine model for human autoimmune uveoretinitis. This regulatory immunity provides induced tolerance to ocular autoantigen, and requires melanocortin 5 receptor (MC5r) expr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Darren J., Preble, Janine, Lee, Stacey, Foster, C. Stephen, Taylor, Andrew W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122918/ https://www.ncbi.nlm.nih.gov/pubmed/27886238 http://dx.doi.org/10.1038/srep37790

Ejemplares similares

A2Ar-dependent PD-1+ and TIGIT+ Treg cells have distinct homing requirements to suppress autoimmune uveitis in mice
por: Peters, Kayleigh, et al.
Publicado: (2023)

Intraocular Implants for the Treatment of Autoimmune Uveitis
por: Lee, Darren J.
Publicado: (2015)

PD-1(+) melanocortin receptor dependent-Treg cells prevent autoimmune disease
por: Muhammad, Fauziyya, et al.
Publicado: (2019)

Review of Systemic Immunosuppression for Autoimmune Uveitis
por: Castiblanco, Claudia, et al.
Publicado: (2014)

Autoimmune and autoinflammatory mechanisms in uveitis
por: Lee, Richard W., et al.
Publicado: (2014)

Microbiome and Autoimmune Uveitis
por: Horai, Reiko, et al.
Publicado: (2019)

Kallistatin Attenuates Experimental Autoimmune Uveitis by Inhibiting Activation of T Cells
por: Muhammad, Fauziyya, et al.
Publicado: (2020)

Apigenin Alleviates Autoimmune Uveitis by Inhibiting Microglia M1 Pro-Inflammatory Polarization
por: Shu, Nan, et al.
Publicado: (2023)

Experimental autoimmune uveitis and other animal models of uveitis: An update
por: Bansal, Svati, et al.
Publicado: (2015)

Immunotherapeutic strategies in autoimmune uveitis
por: Papotto, Pedro Henrique, et al.
Publicado: (2014)

CD73 Expressed on γδ T Cells Shapes Their Regulatory Effect in Experimental Autoimmune Uveitis
por: Liang, Dongchun, et al.
Publicado: (2016)

Parental Uveitis Influences Offspring With an Increased Susceptibility to the Experimental Autoimmune Uveitis
por: Yin, Guangnian, et al.
Publicado: (2020)

P2Y(2)R Deficiency Attenuates Experimental Autoimmune Uveitis Development
por: Relvas, Lia Judice M., et al.
Publicado: (2015)

Antimetabolite Drugs Exhibit Distinctive Immunomodulatory Mechanisms and Effects on the Intestinal Microbiota in Experimental Autoimmune Uveitis
por: Llorenç, Victor, et al.
Publicado: (2022)

Uveitis as a Predictor of Predisposition to Autoimmunity
por: Leibowitz, Jillian A, et al.
Publicado: (2020)

Correction: CD73 Expressed on γδ T Cells Shapes Their Regulatory Effect in Experimental Autoimmune Uveitis
por: Liang, Dongchun, et al.
Publicado: (2016)

Genetic and functional study of StAR (steroidogenic acute regulatory protein) deficiency
por: Kim, Chan Jong
Publicado: (2015)

Deficiency in T follicular regulatory cells promotes autoimmunity
por: Fu, Weiwei, et al.
Publicado: (2018)

Oxidative photoreceptor cell damage in autoimmune uveitis
por: Nguyen, Angeline M., et al.
Publicado: (2010)

Paediatric autoimmune and autoinflammatory conditions associated with uveitis
por: Rahman, Najiha, et al.
Publicado: (2020)

Gut Microbial Alterations Associated With Protection From Autoimmune Uveitis
por: Nakamura, Yukiko K., et al.
Publicado: (2016)

Low Dose Rapamycin Exacerbates Autoimmune Experimental Uveitis
por: Zhang, Zili, et al.
Publicado: (2012)

Amelioration of Experimental Autoimmune Uveitis by Leflunomide in Lewis Rats
por: Fang, Cheng-bo, et al.
Publicado: (2013)

IL-33 attenuates the development of experimental autoimmune uveitis
por: Barbour, Mark, et al.
Publicado: (2014)

Attenuation of Experimental Autoimmune Uveitis in Lewis Rats by Betaine
por: Choi, Yuna, et al.
Publicado: (2021)

Comprehensive Grading System for Experimental Autoimmune Uveitis in Mice
por: Shome, Avik, et al.
Publicado: (2023)

The Role of Interleukin-22 and Its Receptor in the Development and Pathogenesis of Experimental Autoimmune Uveitis
por: Kim, Yejin, et al.
Publicado: (2016)

Deficiency of IL-27 Signaling Exacerbates Experimental Autoimmune Uveitis with Elevated Uveitogenic Th1 and Th17 Responses
por: Wu, Sihan, et al.
Publicado: (2021)

CRALBP is a Highly Prevalent Autoantigen for Human Autoimmune Uveitis
por: Deeg, Cornelia A., et al.
Publicado: (2007)

Direct Detection of Reactive Nitrogen Species in Experimental Autoimmune Uveitis
por: Bae, Sun Ryang, et al.
Publicado: (2007)

Cytokines and Biologics in non-infectious autoimmune uveitis: Bench to Bedside
por: Agrawal, Rupesh, et al.
Publicado: (2014)

Interleukin 35-Producing Exosomes Suppress Neuroinflammation and Autoimmune Uveitis
por: Kang, Minkyung, et al.
Publicado: (2020)

High Ambient Temperature Aggravates Experimental Autoimmune Uveitis Symptoms
por: Pan, Su, et al.
Publicado: (2021)

Cytokines that Modulate the Differentiation of Th17 Cells in Autoimmune Uveitis
por: Guo, Kailei, et al.
Publicado: (2021)

Integrated Transcriptome Analysis of Iris Tissues in Experimental Autoimmune Uveitis
por: Li, Dan, et al.
Publicado: (2022)

Systematic review of studies comparing infliximab and adalimumab in autoimmune uveitis
por: Mase, Oliver, et al.
Publicado: (2023)

Clinical Remission of Sight-Threatening Non-Infectious Uveitis Is Characterized by an Upregulation of Peripheral T-Regulatory Cell Polarized Towards T-bet and TIGIT
por: Gilbert, Rose M., et al.
Publicado: (2018)

Ex-vivo tolerogenic F4/80(+) antigen-presenting cells (APC) induce efferent CD8(+) regulatory T cell-dependent suppression of experimental autoimmune uveitis
por: Hsu, S-M, et al.
Publicado: (2014)

Management of pediatric uveitis
por: Wentworth, Bailey A., et al.
Publicado: (2014)

Treatment of ARS deficiencies with specific amino acids
por: Kok, Gautam, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ctte3lngc8k3kurn6okirl2obe