Neil3 induced neurogenesis protects against prion disease during the clinical phase

Base excision repair (BER) is the major pathway for repair of oxidative DNA damage. Mice with genetic knockout of the BER enzyme Neil3 display compromised neurogenesis in the sub-ventricular zone of the lateral ventricle and sub-granular layer of the dentate gyrus of the hippocampus. To elucidate th...

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Detalles Bibliográficos
Autores principales: Jalland, Clara M. O., Scheffler, Katja, Benestad, Sylvie L., Moldal, Torfinn, Ersdal, Cecilie, Gunnes, Gjermund, Suganthan, Rajikala, Bjørås, Magnar, Tranulis, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122945/
https://www.ncbi.nlm.nih.gov/pubmed/27886261
http://dx.doi.org/10.1038/srep37844

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