Macrophage-dependent IL-1β production induces cardiac arrhythmias in diabetic mice

Diabetes mellitus (DM) encompasses a multitude of secondary disorders, including heart disease. One of the most frequent and potentially life threatening disorders of DM-induced heart disease is ventricular tachycardia (VT). Here we show that toll-like receptor 2 (TLR2) and NLRP3 inflammasome activa...

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Detalles Bibliográficos
Autores principales: Monnerat, Gustavo, Alarcón, Micaela L., Vasconcellos, Luiz R., Hochman-Mendez, Camila, Brasil, Guilherme, Bassani, Rosana A., Casis, Oscar, Malan, Daniela, Travassos, Leonardo H., Sepúlveda, Marisa, Burgos, Juan Ignacio, Vila-Petroff, Martin, Dutra, Fabiano F., Bozza, Marcelo T., Paiva, Claudia N., Carvalho, Adriana Bastos, Bonomo, Adriana, Fleischmann, Bernd K., de Carvalho, Antonio Carlos Campos, Medei, Emiliano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123037/
https://www.ncbi.nlm.nih.gov/pubmed/27882934
http://dx.doi.org/10.1038/ncomms13344

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