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Comparative genomics meets topology: a novel view on genome median and halving problems

BACKGROUND: Genome median and genome halving are combinatorial optimization problems that aim at reconstruction of ancestral genomes by minimizing the number of evolutionary events between them and genomes of the extant species. While these problems have been widely studied in past decades, their so...

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Detalles Bibliográficos
Autores principales: Alexeev, Nikita, Avdeyev, Pavel, Alekseyev, Max A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123253/
https://www.ncbi.nlm.nih.gov/pubmed/28185564
http://dx.doi.org/10.1186/s12859-016-1263-7