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ampliMethProfiler: a pipeline for the analysis of CpG methylation profiles of targeted deep bisulfite sequenced amplicons
BACKGROUND: CpG sites in an individual molecule may exist in a binary state (methylated or unmethylated) and each individual DNA molecule, containing a certain number of CpGs, is a combination of these states defining an epihaplotype. Classic quantification based approaches to study DNA methylation...
Autores principales: | Scala, Giovanni, Affinito, Ornella, Palumbo, Domenico, Florio, Ermanno, Monticelli, Antonella, Miele, Gennaro, Chiariotti, Lorenzo, Cocozza, Sergio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123276/ https://www.ncbi.nlm.nih.gov/pubmed/27884103 http://dx.doi.org/10.1186/s12859-016-1380-3 |
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