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Assisted transcriptome reconstruction and splicing orthology

BACKGROUND: Transcriptome reconstruction, defined as the identification of all protein isoforms that may be expressed by a gene, is a notably difficult computational task. With real data, the best methods based on RNA-seq data identify barely 21 % of the expressed transcripts. While waiting for algo...

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Detalles Bibliográficos
Autores principales: Blanquart, Samuel, Varré, Jean-Stéphane, Guertin, Paul, Perrin, Amandine, Bergeron, Anne, Swenson, Krister M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123294/
https://www.ncbi.nlm.nih.gov/pubmed/28185551
http://dx.doi.org/10.1186/s12864-016-3103-6