HPV16 integration probably contributes to cervical oncogenesis through interrupting tumor suppressor genes and inducing chromosome instability

BACKGROUND: The integration of human papilloma virus (HPV) into host genome is one of the critical steps that lead to the progression of precancerous lesion into cancer. However, the mechanisms and consequences of such integration events are poorly understood. This study aims to explore those questi...

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Detalles Bibliográficos
Autores principales: Zhao, Jun-Wei, Fang, Fang, Guo, Yi, Zhu, Tai-Lin, Yu, Yun-Yun, Kong, Fan-Fei, Han, Ling-Fei, Chen, Dong-Sheng, Li, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123399/
https://www.ncbi.nlm.nih.gov/pubmed/27884161
http://dx.doi.org/10.1186/s13046-016-0454-4

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