Loss of Fractalkine Signaling Exacerbates Axon Transport Dysfunction in a Chronic Model of Glaucoma

Neurodegeneration in glaucoma results in decline and loss of retinal ganglion cells (RGCs), and is associated with activation of myeloid cells such as microglia and macrophages. The chemokine fractalkine (FKN or Cx3cl1) mediates communication from neurons to myeloid cells. Signaling through its rece...

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Detalles Bibliográficos
Autores principales: Breen, Kevin T., Anderson, Sarah R., Steele, Michael R., Calkins, David J., Bosco, Alejandra, Vetter, Monica L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123443/
https://www.ncbi.nlm.nih.gov/pubmed/27932942
http://dx.doi.org/10.3389/fnins.2016.00526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123443/
https://www.ncbi.nlm.nih.gov/pubmed/27932942
http://dx.doi.org/10.3389/fnins.2016.00526

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