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N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection
The RNA modification N6-methyladenosine (m(6)A) post-transcriptionally regulates RNA function. The cellular machinery that controls m(6)A includes methyltransferases and demethylases that add or remove this modification, as well as m(6)A-binding YTHDF proteins that promote the translation or degrada...
Autores principales: | Gokhale, Nandan S., McIntyre, Alexa B.R., McFadden, Michael J., Roder, Allison E., Kennedy, Edward M., Gandara, Jorge A., Hopcraft, Sharon E., Quicke, Kendra M., Vazquez, Christine, Willer, Jason, Ilkayeva, Olga R., Law, Brittany A., Holley, Christopher L., Garcia-Blanco, Mariano A., Evans, Matthew J., Suthar, Mehul S., Bradrick, Shelton S., Mason, Christopher E., Horner, Stacy M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123813/ https://www.ncbi.nlm.nih.gov/pubmed/27773535 http://dx.doi.org/10.1016/j.chom.2016.09.015 |
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