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N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection

The RNA modification N6-methyladenosine (m(6)A) post-transcriptionally regulates RNA function. The cellular machinery that controls m(6)A includes methyltransferases and demethylases that add or remove this modification, as well as m(6)A-binding YTHDF proteins that promote the translation or degrada...

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Detalles Bibliográficos
Autores principales: Gokhale, Nandan S., McIntyre, Alexa B.R., McFadden, Michael J., Roder, Allison E., Kennedy, Edward M., Gandara, Jorge A., Hopcraft, Sharon E., Quicke, Kendra M., Vazquez, Christine, Willer, Jason, Ilkayeva, Olga R., Law, Brittany A., Holley, Christopher L., Garcia-Blanco, Mariano A., Evans, Matthew J., Suthar, Mehul S., Bradrick, Shelton S., Mason, Christopher E., Horner, Stacy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123813/
https://www.ncbi.nlm.nih.gov/pubmed/27773535
http://dx.doi.org/10.1016/j.chom.2016.09.015

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