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Intranasal administration of RSV antigen-expressing MCMV elicits robust tissue-resident effector and effector memory CD8+ T cells in the lung

Cytomegalovirus vectors are promising delivery vehicles for vaccine strategies that aim to elicit effector CD8+ T cells. To determine how the route of immunization affects CD8+ T cell responses in the lungs of mice vaccinated with a murine cytomegalovirus vector expressing the respiratory syncytial...

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Detalles Bibliográficos
Autores principales: Morabito, Kaitlyn M., Ruckwardt, Tracy R., Redwood, Alec J., Moin, Syed M., Price, David A., Graham, Barney S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123975/
https://www.ncbi.nlm.nih.gov/pubmed/27220815
http://dx.doi.org/10.1038/mi.2016.48