Antitumor activity of TY-011 against gastric cancer by inhibiting Aurora A, Aurora B and VEGFR2 kinases

BACKGROUND: Overexpression of Aurora A and B has been reported in a wide range of tumor types, including gastric cancer. Anti-angiogenesis has been considered as an important therapeutic modality in advanced gastric cancer. Here we identified a novel compound TY-011 with promising antitumor activity...

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Detalles Bibliográficos
Autores principales: Liu, Wang, Lu, Yu, Chai, Xiaoping, Liu, Xiao, Zhu, Tong, Wu, Xihan, Fang, Yanfen, Liu, Xuan, Zhang, Xiongwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124248/
https://www.ncbi.nlm.nih.gov/pubmed/27887633
http://dx.doi.org/10.1186/s13046-016-0464-2

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