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Mitochondrial replacement approaches: challenges for clinical implementation

The advent of mitochondrial replacement techniques poses many scientific, regulatory, and ethical questions. Previous studies suggest good safety and efficacy profiles of these techniques, but challenges remain for clinical implementation and international consensus is needed on the regulation of th...

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Detalles Bibliográficos
Autores principales: Klopstock, Thomas, Klopstock, Barbara, Prokisch, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124262/
https://www.ncbi.nlm.nih.gov/pubmed/27887638
http://dx.doi.org/10.1186/s13073-016-0380-2
Descripción
Sumario:The advent of mitochondrial replacement techniques poses many scientific, regulatory, and ethical questions. Previous studies suggest good safety and efficacy profiles of these techniques, but challenges remain for clinical implementation and international consensus is needed on the regulation of these approaches.