Mitochondrial replacement approaches: challenges for clinical implementation

The advent of mitochondrial replacement techniques poses many scientific, regulatory, and ethical questions. Previous studies suggest good safety and efficacy profiles of these techniques, but challenges remain for clinical implementation and international consensus is needed on the regulation of th...

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Detalles Bibliográficos
Autores principales: Klopstock, Thomas, Klopstock, Barbara, Prokisch, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124262/
https://www.ncbi.nlm.nih.gov/pubmed/27887638
http://dx.doi.org/10.1186/s13073-016-0380-2
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author Klopstock, Thomas
Klopstock, Barbara
Prokisch, Holger
author_facet Klopstock, Thomas
Klopstock, Barbara
Prokisch, Holger
author_sort Klopstock, Thomas
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description The advent of mitochondrial replacement techniques poses many scientific, regulatory, and ethical questions. Previous studies suggest good safety and efficacy profiles of these techniques, but challenges remain for clinical implementation and international consensus is needed on the regulation of these approaches.
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spelling pubmed-51242622016-12-08 Mitochondrial replacement approaches: challenges for clinical implementation Klopstock, Thomas Klopstock, Barbara Prokisch, Holger Genome Med Comment The advent of mitochondrial replacement techniques poses many scientific, regulatory, and ethical questions. Previous studies suggest good safety and efficacy profiles of these techniques, but challenges remain for clinical implementation and international consensus is needed on the regulation of these approaches. BioMed Central 2016-11-25 /pmc/articles/PMC5124262/ /pubmed/27887638 http://dx.doi.org/10.1186/s13073-016-0380-2 Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Comment
Klopstock, Thomas
Klopstock, Barbara
Prokisch, Holger
Mitochondrial replacement approaches: challenges for clinical implementation
title Mitochondrial replacement approaches: challenges for clinical implementation
title_full Mitochondrial replacement approaches: challenges for clinical implementation
title_fullStr Mitochondrial replacement approaches: challenges for clinical implementation
title_full_unstemmed Mitochondrial replacement approaches: challenges for clinical implementation
title_short Mitochondrial replacement approaches: challenges for clinical implementation
title_sort mitochondrial replacement approaches: challenges for clinical implementation
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124262/
https://www.ncbi.nlm.nih.gov/pubmed/27887638
http://dx.doi.org/10.1186/s13073-016-0380-2
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AT prokischholger mitochondrialreplacementapproacheschallengesforclinicalimplementation

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