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Inhibition of autophagy with bafilomycin and chloroquine decreases mitochondrial quality and bioenergetic function in primary neurons

Autophagy is an important cell recycling program responsible for the clearance of damaged or long-lived proteins and organelles. Pharmacological modulators of this pathway have been extensively utilized in a wide range of basic research and pre-clinical studies. Bafilomycin A1 and chloroquine are co...

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Detalles Bibliográficos
Autores principales:	Redmann, Matthew, Benavides, Gloria A., Berryhill, Taylor F., Wani, Willayat Y., Ouyang, Xiaosen, Johnson, Michelle S., Ravi, Saranya, Barnes, Stephen, Darley-Usmar, Victor M., Zhang, Jianhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124357/ https://www.ncbi.nlm.nih.gov/pubmed/27889640 http://dx.doi.org/10.1016/j.redox.2016.11.004

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