Unbearable Pruritus After Withdrawal of (Levo)cetirizine

Twelve cases of unbearable pruritus several days after withdrawal of (levo)cetirizine were reported to the Netherlands Pharmacovigilance Centre Lareb. Eleven reports concerned women and one report concerned a man, aged 19–58 years. These patients had been using these antihistamines continuously for...

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Autores principales: Ekhart, Corine, van der Horst, Petra, van Hunsel, Florence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Case Series
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124431/
https://www.ncbi.nlm.nih.gov/pubmed/27889900
http://dx.doi.org/10.1007/s40800-016-0041-9
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author Ekhart, Corine
van der Horst, Petra
van Hunsel, Florence
author_facet Ekhart, Corine
van der Horst, Petra
van Hunsel, Florence
author_sort Ekhart, Corine
collection PubMed
description Twelve cases of unbearable pruritus several days after withdrawal of (levo)cetirizine were reported to the Netherlands Pharmacovigilance Centre Lareb. Eleven reports concerned women and one report concerned a man, aged 19–58 years. These patients had been using these antihistamines continuously for months or years. They had tried to stop using antihistamines on several occasions but felt unable to withdraw the drug because of the unbearable maddening itch. Finally, slowly tapering the drug or using a short course of corticosteroids helped to withdraw (levo)cetirizine. The Naranjo assessment score ranged from two to four for all the cases, indicating a possible relationship.
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spelling pubmed-51244312016-12-09 Unbearable Pruritus After Withdrawal of (Levo)cetirizine Ekhart, Corine van der Horst, Petra van Hunsel, Florence Drug Saf Case Rep Case Series Twelve cases of unbearable pruritus several days after withdrawal of (levo)cetirizine were reported to the Netherlands Pharmacovigilance Centre Lareb. Eleven reports concerned women and one report concerned a man, aged 19–58 years. These patients had been using these antihistamines continuously for months or years. They had tried to stop using antihistamines on several occasions but felt unable to withdraw the drug because of the unbearable maddening itch. Finally, slowly tapering the drug or using a short course of corticosteroids helped to withdraw (levo)cetirizine. The Naranjo assessment score ranged from two to four for all the cases, indicating a possible relationship. Springer International Publishing 2016-11-26 /pmc/articles/PMC5124431/ /pubmed/27889900 http://dx.doi.org/10.1007/s40800-016-0041-9 Text en © The Author(s) 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Case Series
Ekhart, Corine
van der Horst, Petra
van Hunsel, Florence
Unbearable Pruritus After Withdrawal of (Levo)cetirizine
title Unbearable Pruritus After Withdrawal of (Levo)cetirizine
title_full Unbearable Pruritus After Withdrawal of (Levo)cetirizine
title_fullStr Unbearable Pruritus After Withdrawal of (Levo)cetirizine
title_full_unstemmed Unbearable Pruritus After Withdrawal of (Levo)cetirizine
title_short Unbearable Pruritus After Withdrawal of (Levo)cetirizine
title_sort unbearable pruritus after withdrawal of (levo)cetirizine
topic Case Series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124431/
https://www.ncbi.nlm.nih.gov/pubmed/27889900
http://dx.doi.org/10.1007/s40800-016-0041-9
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