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Stroke as the Sole Manifestation of Takayasu Arteritis in a 15-Year-Old Boy with Latent Tuberculosis

Introduction. Takayasu arteritis is a rare disease affecting the aorta and its main branches, causing arterial claudication and end-organ ischemia, including stroke. The etiology is unknown but is believed to be autoimmune. An association between Takayasu arteritis and tuberculosis has been suggeste...

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Autores principales: Benjaminsen, Espen, Reigstad, Anne, Cengija, Vanja, Lilleby, Vibke, Carlsson, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124653/
https://www.ncbi.nlm.nih.gov/pubmed/27965905
http://dx.doi.org/10.1155/2016/8736248
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author Benjaminsen, Espen
Reigstad, Anne
Cengija, Vanja
Lilleby, Vibke
Carlsson, Maria
author_facet Benjaminsen, Espen
Reigstad, Anne
Cengija, Vanja
Lilleby, Vibke
Carlsson, Maria
author_sort Benjaminsen, Espen
collection PubMed
description Introduction. Takayasu arteritis is a rare disease affecting the aorta and its main branches, causing arterial claudication and end-organ ischemia, including stroke. The etiology is unknown but is believed to be autoimmune. An association between Takayasu arteritis and tuberculosis has been suggested, but the possible relation is unclear. Case Presentation. A 15-year-old Somali boy was diagnosed with latent tuberculosis. He had a lesion in the right lung, and both the tuberculin skin test by the Mantoux method and Quantiferon GOLD test turned out positive. After he suffered a cerebral infarct in the right hemisphere, childhood Takayasu arteritis was diagnosed. The diagnosis was based on diagnostic imaging showing a high-grade stenosis of the origin of the right common carotid artery, an occluded common carotid artery on the left side, a circumferential thickening of the vessel walls in the right and left common carotid artery, and laboratory findings with elevated C-reactive protein. Conclusion. Takayasu arteritis is an uncommon cause of stroke. It should however be kept in mind as a cause of cerebrovascular disease, especially in the young.
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spelling pubmed-51246532016-12-13 Stroke as the Sole Manifestation of Takayasu Arteritis in a 15-Year-Old Boy with Latent Tuberculosis Benjaminsen, Espen Reigstad, Anne Cengija, Vanja Lilleby, Vibke Carlsson, Maria Case Rep Neurol Med Case Report Introduction. Takayasu arteritis is a rare disease affecting the aorta and its main branches, causing arterial claudication and end-organ ischemia, including stroke. The etiology is unknown but is believed to be autoimmune. An association between Takayasu arteritis and tuberculosis has been suggested, but the possible relation is unclear. Case Presentation. A 15-year-old Somali boy was diagnosed with latent tuberculosis. He had a lesion in the right lung, and both the tuberculin skin test by the Mantoux method and Quantiferon GOLD test turned out positive. After he suffered a cerebral infarct in the right hemisphere, childhood Takayasu arteritis was diagnosed. The diagnosis was based on diagnostic imaging showing a high-grade stenosis of the origin of the right common carotid artery, an occluded common carotid artery on the left side, a circumferential thickening of the vessel walls in the right and left common carotid artery, and laboratory findings with elevated C-reactive protein. Conclusion. Takayasu arteritis is an uncommon cause of stroke. It should however be kept in mind as a cause of cerebrovascular disease, especially in the young. Hindawi Publishing Corporation 2016 2016-11-14 /pmc/articles/PMC5124653/ /pubmed/27965905 http://dx.doi.org/10.1155/2016/8736248 Text en Copyright © 2016 Espen Benjaminsen et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Benjaminsen, Espen
Reigstad, Anne
Cengija, Vanja
Lilleby, Vibke
Carlsson, Maria
Stroke as the Sole Manifestation of Takayasu Arteritis in a 15-Year-Old Boy with Latent Tuberculosis
title Stroke as the Sole Manifestation of Takayasu Arteritis in a 15-Year-Old Boy with Latent Tuberculosis
title_full Stroke as the Sole Manifestation of Takayasu Arteritis in a 15-Year-Old Boy with Latent Tuberculosis
title_fullStr Stroke as the Sole Manifestation of Takayasu Arteritis in a 15-Year-Old Boy with Latent Tuberculosis
title_full_unstemmed Stroke as the Sole Manifestation of Takayasu Arteritis in a 15-Year-Old Boy with Latent Tuberculosis
title_short Stroke as the Sole Manifestation of Takayasu Arteritis in a 15-Year-Old Boy with Latent Tuberculosis
title_sort stroke as the sole manifestation of takayasu arteritis in a 15-year-old boy with latent tuberculosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124653/
https://www.ncbi.nlm.nih.gov/pubmed/27965905
http://dx.doi.org/10.1155/2016/8736248
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