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Inhibition of Histone Deacetylase 3 (HDAC3) Mediates Ischemic Preconditioning and Protects Cortical Neurons against Ischemia in Rats

Brain ischemic preconditioning (PC) provides vital insights into the endogenous protection against stroke. Genomic and epigenetic responses to PC condition the brain into a state of ischemic tolerance. Notably, PC induces the elevation of histone acetylation, consistent with evidence that histone de...

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Detalles Bibliográficos
Autores principales: Yang, Xiaoyu, Wu, Qimei, Zhang, Lei, Feng, Linyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124709/
https://www.ncbi.nlm.nih.gov/pubmed/27965534
http://dx.doi.org/10.3389/fnmol.2016.00131