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RU486 Mitigates Hippocampal Pathology Following Status Epilepticus

Status epilepticus (SE) induces rapid hyper-activation of the hypothalamo–pituitary–adrenocortical (HPA) axis. HPA axis hyperactivity results in excess exposure to high levels of circulating glucocorticoids, which are associated with neurotoxicity and depression-like behavior. These observations hav...

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Detalles Bibliográficos
Autores principales: Wulsin, Aynara C., Herman, James P., Danzer, Steve C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124765/
https://www.ncbi.nlm.nih.gov/pubmed/27965624
http://dx.doi.org/10.3389/fneur.2016.00214