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Droplet Merging on a Lab-on-a-Chip Platform by Uniform Magnetic Fields
Droplet microfluidics offers a range of Lab-on-a-chip (LoC) applications. However, wireless and programmable manipulation of such droplets is a challenge. We address this challenge by experimental and modelling studies of uniform magnetic field induced merging of ferrofluid based droplets. Control o...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124862/ https://www.ncbi.nlm.nih.gov/pubmed/27892475 http://dx.doi.org/10.1038/srep37671 |
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author | Varma, V. B. Ray, A. Wang, Z. M. Wang, Z. P. Ramanujan, R. V. |
author_facet | Varma, V. B. Ray, A. Wang, Z. M. Wang, Z. P. Ramanujan, R. V. |
author_sort | Varma, V. B. |
collection | PubMed |
description | Droplet microfluidics offers a range of Lab-on-a-chip (LoC) applications. However, wireless and programmable manipulation of such droplets is a challenge. We address this challenge by experimental and modelling studies of uniform magnetic field induced merging of ferrofluid based droplets. Control of droplet velocity and merging was achieved through uniform magnetic field and flow rate ratio. Conditions for droplet merging with respect to droplet velocity were studied. Merging and mixing of colour dye + magnetite composite droplets was demonstrated. Our experimental and numerical results are in good agreement. These studies are useful for wireless and programmable droplet merging as well as mixing relevant to biosensing, bioassay, microfluidic-based synthesis, reaction kinetics, and magnetochemistry. |
format | Online Article Text |
id | pubmed-5124862 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-51248622016-12-08 Droplet Merging on a Lab-on-a-Chip Platform by Uniform Magnetic Fields Varma, V. B. Ray, A. Wang, Z. M. Wang, Z. P. Ramanujan, R. V. Sci Rep Article Droplet microfluidics offers a range of Lab-on-a-chip (LoC) applications. However, wireless and programmable manipulation of such droplets is a challenge. We address this challenge by experimental and modelling studies of uniform magnetic field induced merging of ferrofluid based droplets. Control of droplet velocity and merging was achieved through uniform magnetic field and flow rate ratio. Conditions for droplet merging with respect to droplet velocity were studied. Merging and mixing of colour dye + magnetite composite droplets was demonstrated. Our experimental and numerical results are in good agreement. These studies are useful for wireless and programmable droplet merging as well as mixing relevant to biosensing, bioassay, microfluidic-based synthesis, reaction kinetics, and magnetochemistry. Nature Publishing Group 2016-11-28 /pmc/articles/PMC5124862/ /pubmed/27892475 http://dx.doi.org/10.1038/srep37671 Text en Copyright © 2016, The Author(s) http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
spellingShingle | Article Varma, V. B. Ray, A. Wang, Z. M. Wang, Z. P. Ramanujan, R. V. Droplet Merging on a Lab-on-a-Chip Platform by Uniform Magnetic Fields |
title | Droplet Merging on a Lab-on-a-Chip Platform by Uniform Magnetic Fields |
title_full | Droplet Merging on a Lab-on-a-Chip Platform by Uniform Magnetic Fields |
title_fullStr | Droplet Merging on a Lab-on-a-Chip Platform by Uniform Magnetic Fields |
title_full_unstemmed | Droplet Merging on a Lab-on-a-Chip Platform by Uniform Magnetic Fields |
title_short | Droplet Merging on a Lab-on-a-Chip Platform by Uniform Magnetic Fields |
title_sort | droplet merging on a lab-on-a-chip platform by uniform magnetic fields |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124862/ https://www.ncbi.nlm.nih.gov/pubmed/27892475 http://dx.doi.org/10.1038/srep37671 |
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