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Functional brain alterations in anorexia nervosa: a scoping review
BACKGROUND: Neuroimaging allows for the identification of brain abnormalities and alterations that are associated with anorexia nervosa (AN). We performed a scoping review to map out the extent and nature of recent research activity on functional magnetic resonance imaging (fMRI) in individuals diag...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125031/ https://www.ncbi.nlm.nih.gov/pubmed/27933159 http://dx.doi.org/10.1186/s40337-016-0118-y |
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author | Fuglset, Tone Seim Landrø, Nils Inge Reas, Deborah Lynn Rø, Øyvind |
author_facet | Fuglset, Tone Seim Landrø, Nils Inge Reas, Deborah Lynn Rø, Øyvind |
author_sort | Fuglset, Tone Seim |
collection | PubMed |
description | BACKGROUND: Neuroimaging allows for the identification of brain abnormalities and alterations that are associated with anorexia nervosa (AN). We performed a scoping review to map out the extent and nature of recent research activity on functional magnetic resonance imaging (fMRI) in individuals diagnosed with, or recovered from, AN (AN-REC). MAIN TEXT: A literature search of PubMed, Psychinfo and Embase was conducted using the search terms “anorexia nervosa” AND “functional magnetic resonance imaging.” We included fMRI studies that involved a comparison between individuals with AN or AN-REC and healthy controls published in English language between 2010 and 2015. A total of 49 papers were included, regardless of the experimental stimuli or paradigm. CONCLUSIONS: Findings varied considerably across studies, reflecting methodological differences in study design, such as sample differences and experimental paradigms. Collectively, studies published during the past five years suggest altered activation in regions related to the fronto-striato and the limbic circuits, which are theorized to have an important role in the pathophysiology of AN. |
format | Online Article Text |
id | pubmed-5125031 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-51250312016-12-08 Functional brain alterations in anorexia nervosa: a scoping review Fuglset, Tone Seim Landrø, Nils Inge Reas, Deborah Lynn Rø, Øyvind J Eat Disord Review BACKGROUND: Neuroimaging allows for the identification of brain abnormalities and alterations that are associated with anorexia nervosa (AN). We performed a scoping review to map out the extent and nature of recent research activity on functional magnetic resonance imaging (fMRI) in individuals diagnosed with, or recovered from, AN (AN-REC). MAIN TEXT: A literature search of PubMed, Psychinfo and Embase was conducted using the search terms “anorexia nervosa” AND “functional magnetic resonance imaging.” We included fMRI studies that involved a comparison between individuals with AN or AN-REC and healthy controls published in English language between 2010 and 2015. A total of 49 papers were included, regardless of the experimental stimuli or paradigm. CONCLUSIONS: Findings varied considerably across studies, reflecting methodological differences in study design, such as sample differences and experimental paradigms. Collectively, studies published during the past five years suggest altered activation in regions related to the fronto-striato and the limbic circuits, which are theorized to have an important role in the pathophysiology of AN. BioMed Central 2016-11-28 /pmc/articles/PMC5125031/ /pubmed/27933159 http://dx.doi.org/10.1186/s40337-016-0118-y Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Review Fuglset, Tone Seim Landrø, Nils Inge Reas, Deborah Lynn Rø, Øyvind Functional brain alterations in anorexia nervosa: a scoping review |
title | Functional brain alterations in anorexia nervosa: a scoping review |
title_full | Functional brain alterations in anorexia nervosa: a scoping review |
title_fullStr | Functional brain alterations in anorexia nervosa: a scoping review |
title_full_unstemmed | Functional brain alterations in anorexia nervosa: a scoping review |
title_short | Functional brain alterations in anorexia nervosa: a scoping review |
title_sort | functional brain alterations in anorexia nervosa: a scoping review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125031/ https://www.ncbi.nlm.nih.gov/pubmed/27933159 http://dx.doi.org/10.1186/s40337-016-0118-y |
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