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Streptococcus pneumoniae disrupts pulmonary immune defence via elastase release following pneumolysin-dependent neutrophil lysis

Streptococcus pneumoniae is a leading cause of bacterial pneumonia and is the principal cause of morbidity and mortality worldwide. Previous studies suggested that excessive activation of neutrophils results in the release of neutrophil elastase, which contributes to lung injury in severe pneumonia....

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Detalles Bibliográficos
Autores principales: Domon, Hisanori, Oda, Masataka, Maekawa, Tomoki, Nagai, Kosuke, Takeda, Wataru, Terao, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125098/
https://www.ncbi.nlm.nih.gov/pubmed/27892542
http://dx.doi.org/10.1038/srep38013