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Streptococcus pneumoniae disrupts pulmonary immune defence via elastase release following pneumolysin-dependent neutrophil lysis
Streptococcus pneumoniae is a leading cause of bacterial pneumonia and is the principal cause of morbidity and mortality worldwide. Previous studies suggested that excessive activation of neutrophils results in the release of neutrophil elastase, which contributes to lung injury in severe pneumonia....
Autores principales: | Domon, Hisanori, Oda, Masataka, Maekawa, Tomoki, Nagai, Kosuke, Takeda, Wataru, Terao, Yutaka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125098/ https://www.ncbi.nlm.nih.gov/pubmed/27892542 http://dx.doi.org/10.1038/srep38013 |
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