Cargando…
A randomized and blinded comparison of qPCR and NGS-based detection of aneuploidy in a cell line mixture model of blastocyst biopsy mosaicism
PURPOSE: A subset of preimplantation stage embryos may possess mosaicism of chromosomal constitution, representing a possible limitation to the clinical predictive value of comprehensive chromosome screening (CCS) from a single biopsy. However, contemporary methods of CCS may be capable of predictin...
Autores principales: | Goodrich, David, Tao, Xin, Bohrer, Chelsea, Lonczak, Agnieszka, Xing, Tongji, Zimmerman, Rebekah, Zhan, Yiping, Scott Jr, Richard T., Treff, Nathan R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125146/ https://www.ncbi.nlm.nih.gov/pubmed/27497716 http://dx.doi.org/10.1007/s10815-016-0784-3 |
Ejemplares similares
-
Evaluation of comprehensive chromosome screening platforms for the detection of mosaic segmental aneuploidy
por: Goodrich, David, et al.
Publicado: (2017) -
Trophectoderm biopsy protocols may impact the rate of mosaic blastocysts in cycles with pre-implantation genetic testing for aneuploidy
por: Xiong, Shun, et al.
Publicado: (2021) -
Preimplantation genetic testing for aneuploidy: A review of published blastocyst reanalysis concordance data
por: Marin, Diego, et al.
Publicado: (2020) -
SNP microarray-based 24 chromosome aneuploidy screening demonstrates that cleavage-stage FISH poorly predicts aneuploidy in embryos that develop to morphologically normal blastocysts
por: Northrop, L.E., et al.
Publicado: (2010) -
Optimized NGS Approach for Detection of Aneuploidies and Mosaicism in PGT-A and Imbalances in PGT-SR
por: García-Pascual, Carmen M., et al.
Publicado: (2020)