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Therapy-resistant septic olecranon bursitis due to Mycobacterium gordonae

Introduction: Septic olecranon bursitis due to atypical mycobacteria is rare. An insidious beginning can delay diagnosis and treatment. Antibacterial therapy recommendations are not well-defined for bursitis caused by atypical mycobacteria. We present a rare case of olecranon bursitis caused by Myco...

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Autores principales: Konrads, Christian, Rückl, Kilian, El Tabbakh, Mohammed, Rudert, Maximilian, Kircher, Stefan, Plumhoff, Piet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: EDP Sciences 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125158/
https://www.ncbi.nlm.nih.gov/pubmed/27892398
http://dx.doi.org/10.1051/sicotj/2016030
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author Konrads, Christian
Rückl, Kilian
El Tabbakh, Mohammed
Rudert, Maximilian
Kircher, Stefan
Plumhoff, Piet
author_facet Konrads, Christian
Rückl, Kilian
El Tabbakh, Mohammed
Rudert, Maximilian
Kircher, Stefan
Plumhoff, Piet
author_sort Konrads, Christian
collection PubMed
description Introduction: Septic olecranon bursitis due to atypical mycobacteria is rare. An insidious beginning can delay diagnosis and treatment. Antibacterial therapy recommendations are not well-defined for bursitis caused by atypical mycobacteria. We present a rare case of olecranon bursitis caused by Mycobacterium gordonae, reporting our experiences regarding pathogen identification and antibiotic therapy, which differs from regimes used in common septic bursitis mostly caused by staphylococcus aureus. Methods: A 35-year-old male with bursitis olecrani received open bursectomy. Microbiological culture did not reveal bacteria. Due to wound healing complications revision surgery was performed four weeks postoperatively. Finally, Mycobacterium gordonae was identified by PCR and an antibiogram could be developed. A triple antimicrobial combination therapy with Rifampicin, Clarithromycin, and Ethambutol was administered systemically for 12 months. The patient was followed-up for 24 months. Results: After the second operation with pathogen identification and antibiotic combination therapy the wound healed without any additional complications. At last follow-up 24 months after the first surgery with bursectomy and 23 months after revision surgery with debridement, the patient was still pain free with no significant clinical findings or tenderness to touch at the operation site. Elbow range of motion was full. Discussion: As septic bursitis can be caused by many different and sometimes rare and difficult to identify bacteria, intraoperative probes should be taken and histopathological and microbiological analysis should be conducted, including PCR. In a young man with olecranon bursitis due to Mycobacterium gordonae surgical treatment and an antibiotic combination therapy showed a good clinical outcome after one and two years.
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spelling pubmed-51251582016-12-09 Therapy-resistant septic olecranon bursitis due to Mycobacterium gordonae Konrads, Christian Rückl, Kilian El Tabbakh, Mohammed Rudert, Maximilian Kircher, Stefan Plumhoff, Piet SICOT J Case Report Introduction: Septic olecranon bursitis due to atypical mycobacteria is rare. An insidious beginning can delay diagnosis and treatment. Antibacterial therapy recommendations are not well-defined for bursitis caused by atypical mycobacteria. We present a rare case of olecranon bursitis caused by Mycobacterium gordonae, reporting our experiences regarding pathogen identification and antibiotic therapy, which differs from regimes used in common septic bursitis mostly caused by staphylococcus aureus. Methods: A 35-year-old male with bursitis olecrani received open bursectomy. Microbiological culture did not reveal bacteria. Due to wound healing complications revision surgery was performed four weeks postoperatively. Finally, Mycobacterium gordonae was identified by PCR and an antibiogram could be developed. A triple antimicrobial combination therapy with Rifampicin, Clarithromycin, and Ethambutol was administered systemically for 12 months. The patient was followed-up for 24 months. Results: After the second operation with pathogen identification and antibiotic combination therapy the wound healed without any additional complications. At last follow-up 24 months after the first surgery with bursectomy and 23 months after revision surgery with debridement, the patient was still pain free with no significant clinical findings or tenderness to touch at the operation site. Elbow range of motion was full. Discussion: As septic bursitis can be caused by many different and sometimes rare and difficult to identify bacteria, intraoperative probes should be taken and histopathological and microbiological analysis should be conducted, including PCR. In a young man with olecranon bursitis due to Mycobacterium gordonae surgical treatment and an antibiotic combination therapy showed a good clinical outcome after one and two years. EDP Sciences 2016-11-29 /pmc/articles/PMC5125158/ /pubmed/27892398 http://dx.doi.org/10.1051/sicotj/2016030 Text en © The Authors, published by EDP Sciences, 2016 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Konrads, Christian
Rückl, Kilian
El Tabbakh, Mohammed
Rudert, Maximilian
Kircher, Stefan
Plumhoff, Piet
Therapy-resistant septic olecranon bursitis due to Mycobacterium gordonae
title Therapy-resistant septic olecranon bursitis due to Mycobacterium gordonae
title_full Therapy-resistant septic olecranon bursitis due to Mycobacterium gordonae
title_fullStr Therapy-resistant septic olecranon bursitis due to Mycobacterium gordonae
title_full_unstemmed Therapy-resistant septic olecranon bursitis due to Mycobacterium gordonae
title_short Therapy-resistant septic olecranon bursitis due to Mycobacterium gordonae
title_sort therapy-resistant septic olecranon bursitis due to mycobacterium gordonae
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125158/
https://www.ncbi.nlm.nih.gov/pubmed/27892398
http://dx.doi.org/10.1051/sicotj/2016030
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