Dendritic cell function and pathogen-specific T cell immunity are inhibited in mice administered levonorgestrel prior to intranasal Chlamydia trachomatis infection

The growing popularity of levonorgestrel (LNG)-releasing intra-uterine systems for long-acting reversible contraception provides strong impetus to define immunomodulatory properties of this exogenous progestin. In initial in vitro studies herein, we found LNG significantly impaired activation of hum...

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Detalles Bibliográficos
Autores principales: Quispe Calla, Nirk E., Vicetti Miguel, Rodolfo D., Mei, Ao, Fan, Shumin, Gilmore, Jocelyn R., Cherpes, Thomas L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125275/
https://www.ncbi.nlm.nih.gov/pubmed/27892938
http://dx.doi.org/10.1038/srep37723

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