Evaluating side effects of nanoparticle‐mediated siRNA delivery to mesenchymal stem cells using next generation sequencing and enrichment analysis

RNA interference has immense potential to modulate cell functions. However, effective delivery of small interfering RNA (siRNA) while avoiding deleterious side effects has proven challenging. This study investigates both intended and unintended effects of diblock copolymer nanoparticle (NP) delivery...

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Detalles Bibliográficos
Autores principales: Malcolm, Dominic W., Sorrells, Janet E., Van Twisk, Daniel, Thakar, Juilee, Benoit, Danielle S. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125403/
https://www.ncbi.nlm.nih.gov/pubmed/27981244
http://dx.doi.org/10.1002/btm2.10035

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