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Maintenance of Taste Organs Is Strictly Dependent on Epithelial Hedgehog/GLI Signaling

For homeostasis, lingual taste papilla organs require regulation of epithelial cell survival and renewal, with sustained innervation and stromal interactions. To investigate a role for Hedgehog/GLI signaling in adult taste organs we used a panel of conditional mouse models to manipulate GLI activity...

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Detalles Bibliográficos
Autores principales:	Ermilov, Alexandre N., Kumari, Archana, Li, Libo, Joiner, Ariell M., Grachtchouk, Marina A., Allen, Benjamin L., Dlugosz, Andrzej A., Mistretta, Charlotte M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125561/ https://www.ncbi.nlm.nih.gov/pubmed/27893742 http://dx.doi.org/10.1371/journal.pgen.1006442

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