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Assessing Visual Fields in Patients with Retinitis Pigmentosa Using a Novel Microperimeter with Eye Tracking: The MP-3

PURPOSE: The purpose of the current study is to investigate the test-retest reproducibility of visual fields (VFs) measured with the MP-3 microperimeter, in patients with retinitis pigmentosa (RP). METHOD: VFs were twice measured with the MP-3 and also the Humphrey Field Analyzer, using the 10–2 tes...

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Autores principales: Igarashi, Nozomi, Matsuura, Masato, Hashimoto, Yohei, Hirasawa, Kazunori, Murata, Hiroshi, Inoue, Tatsuya, Ryo, Obata, Aihara, Makoto, Asaoka, Ryo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125600/
https://www.ncbi.nlm.nih.gov/pubmed/27893769
http://dx.doi.org/10.1371/journal.pone.0166666
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author Igarashi, Nozomi
Matsuura, Masato
Hashimoto, Yohei
Hirasawa, Kazunori
Murata, Hiroshi
Inoue, Tatsuya
Ryo, Obata
Aihara, Makoto
Asaoka, Ryo
author_facet Igarashi, Nozomi
Matsuura, Masato
Hashimoto, Yohei
Hirasawa, Kazunori
Murata, Hiroshi
Inoue, Tatsuya
Ryo, Obata
Aihara, Makoto
Asaoka, Ryo
author_sort Igarashi, Nozomi
collection PubMed
description PURPOSE: The purpose of the current study is to investigate the test-retest reproducibility of visual fields (VFs) measured with the MP-3 microperimeter, in patients with retinitis pigmentosa (RP). METHOD: VFs were twice measured with the MP-3 and also the Humphrey Field Analyzer, using the 10–2 test grid pattern in both perimeters, in 30 eyes (15 right and 15 left eyes) of 18 RP patients (11 males and 7 females). Test-retest reproducibility was assessed using the mean absolute deviation (MAD) measure at all 68 points in the test grid. Reproducibility was also evaluated using the intraclass correlation coefficient (ICC) of VF sensitivities. RESULT: The mean sensitivity measured in the HFA 10–2 was significantly higher than that measured in the MP-3 in both the first and second VF tests (p <0.0001, linear mixed model). The MAD was 2.4±0.6 [1.1 to 3.6] dB for MP-3 and 2.4±0.9 [1.1 to 5.1] dB for HFA 10–2, which was not significantly different (p = 0.76, linear mixed model). The ICC value associated with the MP-3 VFs was 0.81±0.13 [0.49 to 0.98], which was significantly larger than that observed for the HFA 10–2 VFs: 0.77±0.19 [0.20 to 0.94] (p = 0.043, linear mixed model). CONCLUSION: The MP-3 microperimeter appears to be useful to evaluate central visual function in RP eyes, exhibiting test-retest reproducibility that is equal to, or better than, that observed in HFA 10–2 VFs.
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spelling pubmed-51256002016-12-15 Assessing Visual Fields in Patients with Retinitis Pigmentosa Using a Novel Microperimeter with Eye Tracking: The MP-3 Igarashi, Nozomi Matsuura, Masato Hashimoto, Yohei Hirasawa, Kazunori Murata, Hiroshi Inoue, Tatsuya Ryo, Obata Aihara, Makoto Asaoka, Ryo PLoS One Research Article PURPOSE: The purpose of the current study is to investigate the test-retest reproducibility of visual fields (VFs) measured with the MP-3 microperimeter, in patients with retinitis pigmentosa (RP). METHOD: VFs were twice measured with the MP-3 and also the Humphrey Field Analyzer, using the 10–2 test grid pattern in both perimeters, in 30 eyes (15 right and 15 left eyes) of 18 RP patients (11 males and 7 females). Test-retest reproducibility was assessed using the mean absolute deviation (MAD) measure at all 68 points in the test grid. Reproducibility was also evaluated using the intraclass correlation coefficient (ICC) of VF sensitivities. RESULT: The mean sensitivity measured in the HFA 10–2 was significantly higher than that measured in the MP-3 in both the first and second VF tests (p <0.0001, linear mixed model). The MAD was 2.4±0.6 [1.1 to 3.6] dB for MP-3 and 2.4±0.9 [1.1 to 5.1] dB for HFA 10–2, which was not significantly different (p = 0.76, linear mixed model). The ICC value associated with the MP-3 VFs was 0.81±0.13 [0.49 to 0.98], which was significantly larger than that observed for the HFA 10–2 VFs: 0.77±0.19 [0.20 to 0.94] (p = 0.043, linear mixed model). CONCLUSION: The MP-3 microperimeter appears to be useful to evaluate central visual function in RP eyes, exhibiting test-retest reproducibility that is equal to, or better than, that observed in HFA 10–2 VFs. Public Library of Science 2016-11-28 /pmc/articles/PMC5125600/ /pubmed/27893769 http://dx.doi.org/10.1371/journal.pone.0166666 Text en © 2016 Igarashi et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Igarashi, Nozomi
Matsuura, Masato
Hashimoto, Yohei
Hirasawa, Kazunori
Murata, Hiroshi
Inoue, Tatsuya
Ryo, Obata
Aihara, Makoto
Asaoka, Ryo
Assessing Visual Fields in Patients with Retinitis Pigmentosa Using a Novel Microperimeter with Eye Tracking: The MP-3
title Assessing Visual Fields in Patients with Retinitis Pigmentosa Using a Novel Microperimeter with Eye Tracking: The MP-3
title_full Assessing Visual Fields in Patients with Retinitis Pigmentosa Using a Novel Microperimeter with Eye Tracking: The MP-3
title_fullStr Assessing Visual Fields in Patients with Retinitis Pigmentosa Using a Novel Microperimeter with Eye Tracking: The MP-3
title_full_unstemmed Assessing Visual Fields in Patients with Retinitis Pigmentosa Using a Novel Microperimeter with Eye Tracking: The MP-3
title_short Assessing Visual Fields in Patients with Retinitis Pigmentosa Using a Novel Microperimeter with Eye Tracking: The MP-3
title_sort assessing visual fields in patients with retinitis pigmentosa using a novel microperimeter with eye tracking: the mp-3
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125600/
https://www.ncbi.nlm.nih.gov/pubmed/27893769
http://dx.doi.org/10.1371/journal.pone.0166666
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