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Salvianolic Acid B Alleviates Heart Failure by Inactivating ERK1/2/GATA4 Signaling Pathway after Pressure Overload in Mice
BACKGROUND: Heart failure(HF) is a dangerous disease that affects millions of patients. Radix Salvia is widely used in Chinese clinics to treat heart diseases. Salvianolic acid B(SalB) is the major active component of Radix Salvia. This study investigated the mechanisms of action and effects of SalB...
Autores principales: | Yu, Juan, Chen, Renshan, Tan, Yafang, Wu, Jiashin, Qi, Jianyong, Zhang, Minzhou, Gu, Weiwang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125602/ https://www.ncbi.nlm.nih.gov/pubmed/27893819 http://dx.doi.org/10.1371/journal.pone.0166560 |
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