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Shear-Wave Elastography for the Differential Diagnosis of Breast Papillary Lesions
OBJECTIVE: To evaluate the diagnostic performance of shear-wave elastography (SWE) for the differential diagnosis of breast papillary lesions. METHODS: This study was an institutional review board-approved retrospective study, with a waiver of informed consent. A total of 79 breast papillary lesions...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125677/ https://www.ncbi.nlm.nih.gov/pubmed/27893857 http://dx.doi.org/10.1371/journal.pone.0167118 |
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author | Chung, Jin Lee, Won Kyung Cha, Eun-Suk Lee, Jee Eun Kim, Jeoung Hyun Ryu, Young Hoon |
author_facet | Chung, Jin Lee, Won Kyung Cha, Eun-Suk Lee, Jee Eun Kim, Jeoung Hyun Ryu, Young Hoon |
author_sort | Chung, Jin |
collection | PubMed |
description | OBJECTIVE: To evaluate the diagnostic performance of shear-wave elastography (SWE) for the differential diagnosis of breast papillary lesions. METHODS: This study was an institutional review board-approved retrospective study, with a waiver of informed consent. A total of 79 breast papillary lesions in 71 consecutive women underwent ultrasound and SWE prior to biopsy. Ultrasound features and quantitative SWE parameters were recorded for each lesion. All lesions were surgically excised or excised using an ultrasound-guided vacuum-assisted method. The diagnostic performances of the quantitative SWE parameters were compared using the area under the receiver operating characteristic curve (AUC). RESULTS: Of the 79 lesions, six (7.6%) were malignant and 12 (15.2%) were atypical. Orientation, margin, and the final BI-RADS ultrasound assessments were significantly different for the papillary lesions (p < 0.05). All qualitative SWE parameters were significantly different (p < 0.05). The AUC values for SWE parameters of benign and atypical or malignant papillary lesions ranged from 0.707 to 0.757 (sensitivity, 44.4–94.4%; specificity, 42.6–88.5%). The maximum elasticity and the mean elasticity showed the highest AUC (0.757) to differentiate papillary lesions. CONCLUSION: SWE provides additional information for the differential diagnosis of breast papillary lesions. Quantitative SWE features were helpful to differentiate breast papillary lesions. |
format | Online Article Text |
id | pubmed-5125677 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-51256772016-12-15 Shear-Wave Elastography for the Differential Diagnosis of Breast Papillary Lesions Chung, Jin Lee, Won Kyung Cha, Eun-Suk Lee, Jee Eun Kim, Jeoung Hyun Ryu, Young Hoon PLoS One Research Article OBJECTIVE: To evaluate the diagnostic performance of shear-wave elastography (SWE) for the differential diagnosis of breast papillary lesions. METHODS: This study was an institutional review board-approved retrospective study, with a waiver of informed consent. A total of 79 breast papillary lesions in 71 consecutive women underwent ultrasound and SWE prior to biopsy. Ultrasound features and quantitative SWE parameters were recorded for each lesion. All lesions were surgically excised or excised using an ultrasound-guided vacuum-assisted method. The diagnostic performances of the quantitative SWE parameters were compared using the area under the receiver operating characteristic curve (AUC). RESULTS: Of the 79 lesions, six (7.6%) were malignant and 12 (15.2%) were atypical. Orientation, margin, and the final BI-RADS ultrasound assessments were significantly different for the papillary lesions (p < 0.05). All qualitative SWE parameters were significantly different (p < 0.05). The AUC values for SWE parameters of benign and atypical or malignant papillary lesions ranged from 0.707 to 0.757 (sensitivity, 44.4–94.4%; specificity, 42.6–88.5%). The maximum elasticity and the mean elasticity showed the highest AUC (0.757) to differentiate papillary lesions. CONCLUSION: SWE provides additional information for the differential diagnosis of breast papillary lesions. Quantitative SWE features were helpful to differentiate breast papillary lesions. Public Library of Science 2016-11-28 /pmc/articles/PMC5125677/ /pubmed/27893857 http://dx.doi.org/10.1371/journal.pone.0167118 Text en © 2016 Chung et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Chung, Jin Lee, Won Kyung Cha, Eun-Suk Lee, Jee Eun Kim, Jeoung Hyun Ryu, Young Hoon Shear-Wave Elastography for the Differential Diagnosis of Breast Papillary Lesions |
title | Shear-Wave Elastography for the Differential Diagnosis of Breast Papillary Lesions |
title_full | Shear-Wave Elastography for the Differential Diagnosis of Breast Papillary Lesions |
title_fullStr | Shear-Wave Elastography for the Differential Diagnosis of Breast Papillary Lesions |
title_full_unstemmed | Shear-Wave Elastography for the Differential Diagnosis of Breast Papillary Lesions |
title_short | Shear-Wave Elastography for the Differential Diagnosis of Breast Papillary Lesions |
title_sort | shear-wave elastography for the differential diagnosis of breast papillary lesions |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5125677/ https://www.ncbi.nlm.nih.gov/pubmed/27893857 http://dx.doi.org/10.1371/journal.pone.0167118 |
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